@article{oai:omu.repo.nii.ac.jp:00009248,
 author = {HIROTA, Yoshikatsu and MUKAMOTO, Masafumi and BABA, Tsuyoshi and KODAMA, Hiroshi and AZUMA, Ichiro},
 journal = {Bulletin of the University of Osaka Prefecture. Ser. B, Agriculture and life sciences},
 month = {Mar},
 note = {application/pdf, The activation of head kidney phagocytes was studied in rainbow trout injected with an immunopotentiator muramyl dipeptide (MDP). Phagocytes showed dose-dependent migratory response to zymosan-treated rainbow trout serum in chemotaxis assay using Nuclepore membrane. Phagocytes of MDP-injected fish showed higher degree of chemotactic response than those from control fish, Phagocytic activity against hydrophilic plastic beads was enhanced when zymosan-treated trout serum was added to cultures. The activity increased after injection of MDP to trout. Increased level of superoxide generation was observed in phagocytes from MDP-injected fish compared with those from control fish when the cells were stimulated either with phorbol 12-myristate 13-acetate, Aeromonas salmonicida cell lysate or opsonized zymosan in cytochrome C reduction test., Bulletin of the University of Osaka Prefecture. Ser. B, Agriculture and life sciences. 1993, 45, p.67-74},
 pages = {67--74},
 title = {Effect of Muramyl Dipeptide on Phagocyte Functions in Rainbow Trout (Oncorhynchus mykiss)},
 volume = {45},
 year = {1993}
}